Lillian Siu, MD, FRCPC
Staff Medical Oncologist
Associate Professor, University of Toronto
Princess Margaret Hospital
Bras Family Drug Development Program
610 University Avenue, Suite 5-718
Toronto, Ontario
M5G 2M9
Tel: 416-946-2911
Fax: 416-946-4467
Dr. Lillian Siu is a staff physician in the Department
of Medical Oncology and Hematology at Princess Margaret
Hospital since 1998, and is an associate professor at
the University of Toronto. Dr. Siu is Director of the
Phase I Program and Co-Director of the Robert and Maggie
Bras and Family Drug Development Program at Princess
Margaret Hospital. She graduated from the University
of Toronto, Faculty of Medicine in 1991. After her Fellowship
in Medical Oncology at Princess Margaret Hospital, she
completed Drug Development Fellowships at the Princess
Margaret Hospital and at the University of Texas Science
Center, San Antonio.
Dr. Siu's major research focus is in the area of new
anticancer drug development, particularly with respect
to phase I trials and head and neck malignancies. She
is principal investigator of many phase I, II and III
trials supported by NCI, NCIC and the pharmaceutical
industry. She is the principal investigator of a phase
I cooperative agreement U01 award (2008-2013) sponsored
by the United States NCI which aims to expedite the
access and evaluation of novel anti-cancer agents for
patients, optimize clinical trials design of new agents,
and characterize the effects of new agents on their
targets with clinically relevant endpoints, through
the integration of suitable biochemical, pathological,
immunological, molecular, and/or imaging methods. The
Princess Margaret Hospital Phase I Consortium is the
only recipient of this award outside of the United States.
Dr. Siu is the recipient of numerous awards such as
the Elsie Winifred Crann Award at the University of
Toronto in 2001, Teaching Awards in the Medical Oncology
Fellowship Training Program for five consecutive years.
Nationally, Dr. Siu has been the co-chair of the NCIC
CTG Data Safety Monitoring Committee. Internationally,
Dr. Siu has been a member of the AACR International
Membership Committee, the ASCO Head and Neck Cancer
Scientific Program Committee, and the EORTC Protocol
Review Committee. She is the current Neuroendocrine
Tumor Task Force Chair in the Gastrointestinal Intergroup
Scientific Steering Committee. Dr. Siu has a strong
background in clinical trial methodology and has been
a member of the Program Committees for both the FECS/ASCO/AACR
workshop in Flims, Switzerland and the AACR/ASCO workshop
in Vail, Colorado for the past few years. Both workshops
focus on the training of young researchers in clinical
cancer research methods.
Dr. Siu has published 100 peer-reviewed manuscripts
in journals including Journal of Clinical Oncology and Clinical Cancer Research. She is on the
Editorial Board of Investigational New Drugs and
Journal of Clinical Oncology.



